About us

Welcome to the website of Dr Hanns Lochmüller’s research group in Ottawa, Canada. These pages are maintained by group members to provide an overview of our research and clinical activities.

We focus on scientific, genetic and clinical research into rare neuromuscular disorders and clinical care for patients with these conditions. We aim to understand why small variations in the human genome lead to these frequently disabling, sometimes lethal, and rarely treatable conditions affecting the musculature and nervous system. Our group has a bench-to-bedside translational approach, from identifying underlying genetic defects in patients using deep phenotyping and next-generation sequencing, through unravelling molecular pathways in cell and animal models, to testing new targeted therapies in clinical trials.

Hanns is affiliated with the CHEO Research Institute’s Molecular Biomedicine Program and the CHEO Department of Pediatrics, as well as  the Department of Medicine, Division of Neurology of The Ottawa Hospital and the Department of Cellular and Molecular Medicine and the Brain and Mind Research Institute at the University of Ottawa. His group members work across various of these affiliations and he has close collaborations with many other research groups across the world.

About us

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The team

Team members

Meet the team Kiran Polavarapu Dr. Kiran Polavarapu completed his PhD in 2019 at the National Institute of Mental Health and Neurosciences (NIMHANS) in India....
Researcher using a pipette in a fume hood

Research areas

Our areas of research Although individually uncommon, rare diseases are so numerous that they collectively affect as many as one person in every 17 –...
Rack of newspapers

News

News Oct 25 The power of diagnosis – watch “Yakup’s journey to hope” A genetic diagnosis brings so much to families - and sometimes allows...
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Collaborations

We are a highly collaborative group and our research is founded on strong partnerships with leading investigators, academic groups, patient organizations and pharmaceutical and biotech...
Map of Ottawa showing CHEO-RI location

Contact us

Contact us Mailing address: CHEO Research Institute 401 Smyth Road Ottawa, ON K1H 8L1 Canada   Email addresses: See the profile pages of individual team...