Other inherited neuromuscular conditions

Our research interests often span diseases and encompass a wide range of inherited neuromuscular conditions. Conditions such as DMD and myotonic dystrophy affect hundreds of individuals in Canada, but there are at least another 400 genetically distinct neuromuscular diseases that affect smaller numbers of people. These include mitochondrial myopathies, myofibrillar neuropathies, congenital muscular dystrophies, limb-girdle muscular dystrophies, inherited neuropathies, metabolic myopathies and other complex neurological conditions. Most of these conditions do not have effective therapies, and many families lack a definite molecular diagnosis.

Hanns sees patients with all forms of neuromuscular disease in clinic. Our team’s research into those other less frequent neuromuscular diseases ranges from gene discovery and the elucidation of the underlying pathogenesis to the development of new therapeutic approaches.

Image of stained muscle sections using different staining techniques

Relevant publications