Lochmüller Lab

Professor Hanns Lochmüller is a neurologist and clinical academic specializing in genetic neuromuscular disorders and rare disease. He is Senior Scientist at the Children’s Hospital of Eastern Ontario (CHEO) Research Institute and Professor of Neurology in the University of Ottawa Faculty of Medicine and the Department of Medicine, Division of Neurology at The Ottawa Hospital.

Sally is a Research Associate in the Lochmüller lab, where she leads the basic research team. A senior postdoctoral researcher with experience in Canada and the UK, Sally joined Hanns soon after his appointment in Ottawa and is overseeing the lab setup and expansion.

Emily completed her PhD at Newcastle University in 2019 under the supervision of Professors Hanns Lochmüller and Clarke Slater and joined the Lochmüller lab to continue her work into testing new treatments for CMS.

Rachel completed her PhD at Newcastle University in the UK, where she was involved in the coordination of the RD-Connect data sharing and analysis platform. She is a postdoctoral fellow in the Lochmüller Lab with a research interest in the use of data integration methods for medical genomics and precision medicine in neuromuscular diseases.

Kiran completed his PhD in 2019 at the National Institute of Mental Health and Neurosciences (NIMHANS) in India. His PhD work involved developing next generation sequencing (NGS)-based tests for detection of both copy number variations and point mutations in Duchenne Muscular Dystrophy. He recently joined the Lochmüller Lab as a postdoctoral fellow.

Marc-Olivier Deguise is currently a pediatric resident physician at Children’s Hospital of Eastern Ontario and has been involved with the SMA community through a research lens for the past eight years. He recently joined Dr. Lochmüller’s Lab to contribute to the clinical research aspect of the research program.

Anu is a post-doctoral fellow working on gene therapy for congenital myasthenic syndromes (CMS) and on biomarkers for myotonic dystrophy type 1 (DM1).

Stephen has joined the Lochmüller Lab for his PhD, having just completed an MSc degree looking at post-translational modifications affecting pannexin 1 protein channels in neuroblastoma.

Jarred recently graduated with a BSc (Biology and Biotechnology) and has joined the Lochmüller lab as a Masters student to investigate the genetic causes of congenital myasthenic syndromes.

Following the completion of his Masters degree, Alex started studying Medicine at the University of Ottawa. He has joined the Lochmüller lab to work on a project investigating the therapeutic potential of Smac-mimetic compounds on neuromuscular diseases.

Catherine began her Master’s program in Cellular and Molecular Medicine with a specialization in Human and Molecular Genetics. She is working under the supervision of Dr. Lochmüller to create a zebrafish model for riboflavin transporter deficiency to be used in therapeutic screening.

Rosa joined the Lochmüller Lab in 2019 to contribute to the group’s clinical research activities.

Erin is the Network Manager for NMD4C, the neuromuscular disease network for Canada. She graduated with a BSc in microbiology & immunology and an MSc in pharmacology from Dalhousie University, and a PhD in laboratory medicine & pathobiology from the University of Toronto.

James Davis is the Communications Coordinator for the Neuromuscular Disease Network for Canada (NMD4C) led by Dr. Lochmüller. James holds a Masters Degree in Human Kinetics, and brings experience in network creation from his past work building and facilitating a sport safety network across Canada.