Alexander Manta

Medical Student

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Alex Manta completed a research project with Dr. Lochmüller in 2019, during his medical degree at the University of Ottawa. His research investigated the therapeutic potential of Smac-mimetic compounds on myoblasts from patients with various neuromuscular diseases. He is now completing his medical residency in neurology at the University of Toronto.

Before joining the lab, Alex completed his MSc in the Integrative Neuromuscular Biology Laboratory, part of the Exercise Metabolism Research Group in the Department of Kinesiology at McMaster University under the supervision of Dr. Vladimir Ljubicic. His thesis focused on the exercise biology of myotonic dystrophy type 1.

Alex Manta

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Recent publications

Manta, A, Stouth, DW, Xhuti, D, Chi, L, Rebalka, IA, Kalmar, JM et al.. Chronic exercise mitigates disease mechanisms and improves muscle function in myotonic dystrophy type 1 mice. J Physiol. 2019.597 (5)1361-1381 PMID:30628727

Manta, A, Opingari, E, Saleh, AH, Simunovic, N, Duong, A, Sprague, S et al.. A systematic review of meta-analyses in orthopaedic surgery between 2000 and 2016. Bone Joint J. 2018.100-B (10)1270-1274 PMID:30295532

Ng, SY, Manta, A, Ljubicic, V. Exercise biology of neuromuscular disorders. Appl Physiol Nutr Metab. 2018.43 (11)1194-1206 PMID:29944848

Dial, AG, Ng, SY, Manta, A, Ljubicic, V. The Role of AMPK in Neuromuscular Biology and Disease. Trends Endocrinol Metab. 2018.29 (5)300-312 PMID:29572064

Stouth, DW, Manta, A, Ljubicic, V. Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity. Am J Physiol Cell Physiol. 2018.314 (2)C177-C190 PMID:29092819

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