Ofosu Adjei-Afriyie is a Master’s student in Cellular and Molecular Medicine. Ofosu’s research is focused on insulin resistance in Myotonic Dystrophy Type 1 (DM1). He will attempt to further elucidate and characterize the mechanisms that underlie the pathophysiology of insulin resistance in DM1, by investigating how exercise may impact the insulin resistance in DM1 using DM1-afflicted tissue and cellular models of the disease.
For his undergraduate honours project, Ofosu joined the Lochmüller lab to study the therapeutic effects of MuSK agonist antibodies on mutant AGRIN CMS mice models.
Prior to entering the lab as an honours student, Ofosu conducted research under the supervison of Dr. Adam Rudner. With Dr. Rudner, he has discovered his own M. foliorum bacteriophage and has gone on to annotate and characterize an additional bacteriophage. In the winter of 2021, Ofosu extended his research with Dr. Rudner to investigate an uncharacterized tail assembly chaperone frameshift in bacteriophage Winzigispinne.
