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New Publication: A phase 3 randomized study evaluating sialic acid extended-release for GNE myopathy
…now available to read online. Dr Lochmüller led an international group of investigators in a phase 3 clinical trial sponsored by Ultragenyx Pharmaceutical Inc with full results now published in…
Read MoreThe Lochmüller Lab wins CIHR project award!
We are delighted to announce that our project on congenital myasthenic syndromes (CMS) has been funded in the Canadian Institute for Health Research’s Fall 2018 project grant competition. Through this…
Read MoreNew pan-Canadian neuromuscular network unites doctors, researchers and patients for better research and care
…the network, while management and communications professionals might be interested in one of our open positions with the Lochmüller Lab in Ottawa: see the jobs on the NMD4C website and…
Read MoreGNE myopathy
…and validation of biomarkers for GNE myopathy. In the clinical research area, Hanns has been principal investigator for several natural history and treatment studies in collaboration with the pharma company…
Read MoreCollaborations
…investigator at the CHEO Research Institute. He directs the care of children with neuromuscular disease from a large region of Eastern Ontario and Western Quebec and is principal investigator for…
Read MoreInvitation to submit to special issues of the Journal of Neuromuscular Diseases
…leads to unnecessary duplication of efforts and a waste of resources. This issue is guest edited by Annemieke Aartsma-Rus and Virginia Arechavala-Gomeza and submissions are due by March 2021. JND…
Read MoreMeet the Lochmüller Lab Clinical Team
…information system implementation (Project Fusion) for The Ottawa Hospital and Atlas Alliance hospitals, focusing on launching the Epic research module for Coordinators and Clinicians at the Ottawa Hospital Research Institute….
Read MoreMatthew MacDonald
Matthew joined the team in June 2021 as a Research Coordinator, working on several neuromuscular disease clinical trials for Dr. Lochmüller….
Read MoreCongenital myasthenic syndromes
…of acetylcholine available in the synaptic cleft (for which commonly administered therapies include AChE inhibitors such as pyridostigmine, which inhibits acetylcholine breakdown, and the potassium-channel blocker 3,4-diaminopyridine, which increases the…
Read MoreMarc-Olivier Deguise
Marc-Olivier Deguise is currently a pediatric resident physician at Children’s Hospital of Eastern Ontario and has been involved with the SMA community through a research lens for the past eight…
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